mTOR Signaling in Growth Control and Disease

by Laplante, Mathieu, Sabatini, David M., Sabatini, David M.
Published 2014

Nutrients versus growth factors in mTORC1 activation

by Efeyan, Alejo, Sabatini, David M., Sabatini, David M.
Published 2015

A Radical Role for TOR in Longevity

by Lamming, Dudley W., Sabatini, David M., Sabatini, David M.
Published 2014

A Central Role for mTOR in Lipid Homeostasis

by Lamming, Dudley W., Sabatini, David M., Lamming, Dudley W., Sabatini, David M.
Published 2016

mTORC1 Activates SREBP-1c and Uncouples Lipogenesis From Gluconeogenesis

by Sabatini, David M., Laplante, Mathieu
Published 2011

The TASCC of Secretion

by Zoncu, Roberto, Sabatini, David M.
Published 2013

mTOR and cancer: many loops in one pathway

by Efeyan, Alejo, Sabatini, David M.
Published 2012

Rag proteins regulate amino-acid-induced mTORC1 signalling

by Sancak, Yasemin, Sabatini, David M.
Published 2011

An emerging role of mTOR in lipid biosynthesis

by Laplante, Mathieu, Sabatini, David M.
Published 2012

Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo

by Sheen, Joon-Ho, Zoncu, Roberto, Kim, Dohoon, Sabatini, David M., Sabatini, David M.
Published 2014

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

by Bar-Peled, Liron, Zoncu, Roberto, Sabatini, David M., Schweitzer, Lawrence David, Sabatini, David M.
Published 2014

Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer

by Mihaylova, Maria M., Sabatini, David M., Yilmaz, Omer, Mihaylova, Maria M., Sabatini, David M.
Published 2016

Myeloid-Specific Rictor Deletion Induces M1 Macrophage Polarization and Potentiates In Vivo Pro-Inflammatory Response to Lipopolysaccharide

by Festuccia, William T., Pouliot, Philippe, Bakan, Inan, Sabatini, David M., Laplante, Mathieu, Sabatini, David M.
Published 2014

Rapamycin inhibits mTORC1, but not completely

by Thoreen, Carson C., Sabatini, David M.
Published 2012

Cancer Cell Metabolism: One Hallmark, Many Faces

by Sabatini, David M., Cantor, Jason R.
Published 2015

Growth signaling at the nexus of stem cell life and death

by Wood, Kris C., Sabatini, David M.
Published 2009

mTOR: from growth signal integration to cancer, diabetes and ageing

by Zoncu, Roberto, Efeyan, Alejo, Sabatini, David M.
Published 2012

DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

by Laplante, Mathieu, Horvat, Simon, Festuccia, William T., Birsoy, Kivanc, Prevorsek, Zala, Efeyan, Alejo, Sabatini, David M., Sabatini, David M.
Published 2014

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

by Sengupta, Shomit, Peterson, Timothy R., Sabatini, David M.
Published 2015

Nutrient-sensing mechanisms and pathways

by Efeyan, Alejo, Comb, William C., Sabatini, David M.
Published 2015