Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment

Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment

Antibiotic resistance arising via chromosomal mutations is typically specific to a particular antibiotic or class of antibiotics. We have identified mutations in genes encoding ribosomal components in Mycobacterium smegmatis that confer resistance to several structurally and mechanistically unrelate...

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Main Authors: Gomez, James E, Kaufmann-Malaga, Benjamin B, Wivagg, Carl N, Kim, Peter B, Silvis, Melanie R, Renedo, Nikolai, Ioerger, Thomas R, Ahmad, Rushdy, Livny, Jonathan, Fishbein, Skye, Hung, Deborah T, Carr, Steven A
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2017
Online Access:http://hdl.handle.net/1721.1/109859
https://orcid.org/0000-0002-7203-4299
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http://hdl.handle.net/1721.1/109859
https://orcid.org/0000-0002-7203-4299

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