Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis

Background: The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp virulence, we performed a comparative genomic analysis of Bp K96243 and B. thailandensis (Bt) E264, a closely r...

Full description

Saved in:
Bibliographic Details
Main Authors: Yu, Yiting, Chua, Hui Hoon, Lin, Chi Ho, Sim, Siew Hoon, Lin, Daoxun, Derr, Alan, Engels, Reinhard, DeShazer, David, Birren, Bruce W., Nierman, William C., Tan, Patrick, Kim, H. Stanley
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/58919
Tags: Add Tag
No Tags, Be the first to tag this record!