Reduced Expression of Ribosomal Proteins Relieves MicroRNA-Mediated Repression

MicroRNAs (miRNAs) regulate physiological and pathological processes by inducing posttranscriptional repression of target messenger RNAs (mRNAs) via incompletely understood mechanisms. To discover factors required for human miRNA activity, we performed an RNAi screen using a reporter cell line of mi...

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Bibliographic Details
Main Authors: Janas, Maja M., Love, Tara, Harris, Abigail S., Stevenson, Kristen, Semmelmann, Karlheinz, Shaffer, Jonathan M., Chen, Po-Hao, Doench, John G., Yerramilli, Subrahmanyam V.B.K., Neuberg, Donna S., Iliopoulos, Dimitrios, Novina, Carl D., Wang, Eric T, Housman, David E, Burge, Christopher B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier B.V. 2014
Online Access:http://hdl.handle.net/1721.1/83590
https://orcid.org/0000-0001-5016-0756
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