Apical domain polarization localizes actin–myosin activity to drive ratchet-like apical constriction

Apical constriction promotes epithelia folding, which changes tissue architecture. During Drosophila gastrulation, mesoderm cells exhibit repeated contractile pulses that are stabilized such that cells apically constrict like a ratchet. The transcription factor Twist is required to stabilize cell sh...

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Bibliographic Details
Main Authors: Tworoger, Michael B., Martin, Adam C, Mason, Frank M
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/85570
https://orcid.org/0000-0001-8060-2607
https://orcid.org/0000-0003-1338-494X
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