A Fluorescently Tagged C-Terminal Fragment of p47phox Detects NADPH Oxidase Dynamics during Phagocytosis
The assembly of cytosolic p47phox and p67phox with flavocytochrome b558 at the membrane is crucial for activating the leukocyte NADPH oxidase that generates superoxide for microbial killing. p47phox and p67phox are linked via a high-affinity, tail-to-tail interaction involving a proline-rich region...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | en_US |
| Published: |
2014
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| Subjects: | |
| Online Access: | http://hdl.handle.net/1805/4173 |
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