Operon mRNAs are organized into ORF-centric structures that predict translation efficiency

Bacterial mRNAs are organized into operons consisting of discrete open reading frames (ORFs) in a single polycistronic mRNA. Individual ORFs on the mRNA are differentially translated, with rates varying as much as 100-fold. The signals controlling differential translation are poorly understood. Our...

Full description

Saved in:
Bibliographic Details
Main Authors: Burkhardt, David H, Rouskin, Silvi, Zhang, Yan, Li, Gene-Wei, Weissman, Jonathan S, Gross, Carol A
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: eLife Sciences Publications, Ltd 2018
Online Access:http://hdl.handle.net/1721.1/115142
https://orcid.org/0000-0001-7036-8511

CIC - Centro de Información y Conocimiento Johannes Gutenberg ®