Presynaptic m1 muscarinic receptors are necessary for mGluR LTD in the hippocampus

To investigate the role of M1 muscarininc acetylcholine receptors (m1 receptors) in metabotropic glutamate receptor (mGluR)-mediated long-term depression (LTD), we produced mouse lines in which deletion of the m1 gene is restricted to the forebrain (FB–m1KO) or hippocampal CA3 pyramidal neurons (CA3...

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Bibliographic Details
Main Authors: Kamsler, Ariel, McHugh, Thomas J., Gerber, David, Huang, Shu Ying, Tonegawa, Susumu
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: National Academy of Sciences (U.S.) 2011
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