Pd-Catalyzed O-Arylation of Ethyl Acetohydroximate: Synthesis of O-Arylhydroxylamines and Substituted Benzofurans

An efficient Pd catalyst for the O-arylation of ethyl acetohydroximate with aryl chlorides, bromides, and iodides has been developed. Ethyl acetohydroximate serves as an efficient hydroxylamine equivalent for C−O cross-coupling, thereby allowing for the preparation of O-arylhydroxylamines from simpl...

Full description

Saved in:
Bibliographic Details
Main Authors: Maimone, Thomas, Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2012
Online Access:http://hdl.handle.net/1721.1/72344
https://orcid.org/0000-0003-3875-4775

CIC - Centro de Información y Conocimiento Johannes Gutenberg ®