Cu-Catalyzed Arylation of Phenols: Synthesis of Sterically Hindered and Heteroaryl Diaryl Ethers

Cu-catalyzed O-arylation of phenols with aryl iodides and bromides can be performed under mild condition in DMSO/K3PO4 with use of picolinic acid as the ligand for copper. This method tolerates a variety of functional groups and is effective in the synthesis of hindered diaryl ethers and heteroaryl...

Full description

Saved in:
Bibliographic Details
Main Authors: Maiti, Debabrata, Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society 2012
Online Access:http://hdl.handle.net/1721.1/73472
https://orcid.org/0000-0003-3875-4775

CIC - Centro de Información y Conocimiento Johannes Gutenberg ®