Cascade Palladium Catalysis: A Predictable and Selectable Regiocontrolled Synthesis of N-Arylbenzimidazoles

By choice: The palladium-catalyzed cascade reaction of 2-chloroaryl sulfonates with arylamine and amide nucleophiles provides direct access to N-arylbenzimidazoles. This strategy selectively produces the heterocycles based on chemoselective oxidative addition. 2-Chloroaryl triflates (Tf) produce one...

Full description

Saved in:
Bibliographic Details
Main Authors: Jui, Nathan T., Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: John Wiley & Sons, Inc 2014
Online Access:http://hdl.handle.net/1721.1/85069
https://orcid.org/0000-0003-3875-4775

CIC - Centro de Información y Conocimiento Johannes Gutenberg ®