Unraveling Mechanisms of Persister Formation during Normal Growth

Unraveling Mechanisms of Persister Formation during Normal Growth

Persisters are phenotypic variants present within bacterial populations that exhibit extreme tolerance toward antibiotic stress and are believed to be responsible for chronic and recurrent infections. Despite this clinical importance, the pathways responsible for persister formation during normal gr...

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Bibliographic Details
Main Author: Amato, Stephanie M.
Other Authors: Brynildsen, Mark P.
Format: Academic dissertations (Ph.D.)
Language:English
Published: Princeton, NJ : Princeton University 2015
Subjects:
bacterial persistence
carbon source transition
phenotypic heterogeneity
stringent response
Chemical engineering
Microbiology
Online Access:http://arks.princeton.edu/ark:/88435/dsp01z603r073m
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http://arks.princeton.edu/ark:/88435/dsp01z603r073m

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