Dystrophic spinal deformities in a neurofibromatosis type 1 murine model

Dystrophic spinal deformities in a neurofibromatosis type 1 murine model

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Despite the high prevalence and significant morbidity of spinal anomalies in neurofibromatosis type 1 (NF1), the pathogenesis of these defects remains largely unknown. Here, we present two murine models: Nf1flox/-;PeriCre and Nf1flox/-;Col.2.3Cre mice, which recapitulate spinal deformities seen in t...

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Main Authors: Rhodes, Steven D., Zhang, Wei, Yang, Dalong, Yang, Hao, Chen, Shi, Wu, Xiahoua, Yang, Xianlin, Mohammad, Khalid S., Guise, Theresa A., Bergner, Amanda L., Stevenson, David A., Yang, Feng-Chun
Format: Online
Language:en_US
Published: PLoS 2016
Online Access:Rhodes, S. D., Zhang, W., Yang, D., Yang, H., Chen, S., Wu, X., … Yang, F.-C. (2015). Dystrophic Spinal Deformities in a Neurofibromatosis Type 1 Murine Model. PLoS ONE, 10(3), e0119093. http://doi.org/10.1371/journal.pone.0119093
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Rhodes, S. D., Zhang, W., Yang, D., Yang, H., Chen, S., Wu, X., … Yang, F.-C. (2015). Dystrophic Spinal Deformities in a Neurofibromatosis Type 1 Murine Model. PLoS ONE, 10(3), e0119093. http://doi.org/10.1371/journal.pone.0119093

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