Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer

Cancer cells are known to execute reprogramed metabolism of glucose, amino acids and lipids. Here, we report a significant role of cholesterol metabolism in cancer metastasis. By using label-free Raman spectromicroscopy, we found an aberrant accumulation of cholesteryl ester in human pancreatic canc...

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Bibliographic Details
Main Authors: Li, J., Gu, D., Lee, SS-Y., Song, B., Bandyopadhyay, S., Chen, S., Konieczny, SF., Ratliff, TL., Liu, X., Xie, J., Cheng, J-X.
Format: Online
Language:en_US
Published: SpringerNature 2017
Online Access:Li, J., Gu, D., Lee, S. S.-Y., Song, B., Bandyopadhyay, S., Chen, S., … Cheng, J.-X. (2016). Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer. Oncogene, 35(50), 6378–6388. http://doi.org/10.1038/onc.2016.168
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