Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer
Cancer cells are known to execute reprogramed metabolism of glucose, amino acids and lipids. Here, we report a significant role of cholesterol metabolism in cancer metastasis. By using label-free Raman spectromicroscopy, we found an aberrant accumulation of cholesteryl ester in human pancreatic canc...
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Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | en_US |
Published: |
SpringerNature
2017
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Online Access: | Li, J., Gu, D., Lee, S. S.-Y., Song, B., Bandyopadhyay, S., Chen, S., … Cheng, J.-X. (2016). Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer. Oncogene, 35(50), 6378–6388. http://doi.org/10.1038/onc.2016.168 |
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