Prospective Validation of a 21-Gene Expression Assay in Breast Cancer

BACKGROUND Prior studies with the use of a prospective–retrospective design including archival tumor samples have shown that gene-expression assays provide clinically useful prognostic information. However, a prospectively conducted study in a uniformly treated population provides the highest level...

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Main Authors: Sparano, Joseph A., Gray, Robert J., Makower, Della F., Pritchard, Kathleen I., Albain, Kathy S., Hayes, Daniel F., Geyer, Charles E., Jr., Dees, Elizabeth C., Perez, Edith A., Olson, John A., Jr., Zujewski, JoAnne, Lively, Tracy, Badve, Sunil S., Saphner, Thomas J., Wagner, Lynne I., Whelan, Timothy J., Ellis, Matthew J., Paik, Soonmyung, Wood, William C., Ravdin, Peter, Keane, Maccon M., Gomez Moreno, Henry L., Reddy, Pavan S., Goggins, Timothy F., Mayer, Ingrid A., Brufsky, Adam M., Toppmeyer, Deborah L., Kaklamani, Virginia G., Atkins, James N., Berenberg, Jeffrey L., Sledge, George W.
Format: Online
Language:English
Published: Massachusetts Medical Society 2019
Online Access:Sparano, J. A., Gray, R. J., Makower, D. F., Pritchard, K. I., Albain, K. S., Hayes, D. F., ... & Zujewski, J. (2015). Prospective validation of a 21-gene expression assay in breast cancer. New England Journal of Medicine, 373(21), 2005-2014. http://dx.doi.org/10.1056/NEJMoa1510764
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