Stereoselective pharmacokinetics of stable isotope (+/-)-[13C]-pantoprazole: Implications for a rapid screening phenotype test of CYP2C19 activity
AIMS: We have previously shown that the (±)-[(13) C]-pantoprazole breath test is a promising noninvasive probe of CYP2C19 activity. As part of that trial, plasma, breath test indices and CYP2C19 (*2, *3, and *17) genotype were collected. Here, we examined whether [(13) C]-pantoprazole exhibits en...
Saved in:
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | en_US |
Published: |
Wiley
2015
|
Online Access: | Thacker, D. L., Modak, A., Nguyen, P. D., Flockhart, D. A., & Desta, Z. (2011). Stereoselective Pharmacokinetics of Stable Isotope (+/−)-[13C]-Pantoprazole: Implications for a Rapid Screening Phenotype Test of CYP2C19 Activity. Chirality, 23(10), 904–909. http://doi.org/10.1002/chir.21011 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|