Association of ABCB1, ABCC5 and xanthine oxidase genetic polymorphisms with methotrexate adverse reactions in Mexican pediatric patients with ALL
Background: Acute lymphoblastic leukemia (ALL) is one of the most frequent oncological disorders in pediatric populations. To date, the drug of choice for the treatment of ALL is methotrexate, a drug associated with a high risk of adverse reactions (ADRs). The xanthine oxidase (XO) polymorphisms, 19...
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| Format: | Article |
| Language: | en_US |
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WALTER DE GRUYTER GMBH
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941060132&doi=10.1515%2fdmpt-2015-0011&partnerID=40&md5=57015a17aca03334e165e445138d8fcc http://dspace.ucuenca.edu.ec/handle/123456789/29242 |
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