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1“... involves protein misfolding and aggregation of the primary proteins of the lens, the crystallins. Human γD...”
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2“...-aggregation disease of the human lens often involving the major proteins of the lens, the crystallins. γD...”
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3“...Human γD-crystallin (HγD-Crys) is a two-domain, β-sheet eye lens protein found in the lens nucleus...”
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4“...Age-onset cataracts are believed to be expedited by the accumulation of UV-damaged human γD...”
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5by Callis, Patrik R., King, Jonathan Alan, Chen, Jiejin, Ph. D. Massachusetts Institute of Technology“... of these Trps in human γD-crystallin is very efficiently quenched in the native state by electrostatically...”
Published 2012
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6by Baker, Matthew L., Hryc, Corey F., Zhang, Qinfen, Wu, Weimin, Jakana, Joanita, Haase-Pettingell, Cameron, Afonine, Pavel V., Adams, Paul D., King, Jonathan Alan, Jiang, Wen, Chiu, WahGet full text
Published 2014
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7by Hryc, Corey F., Chen, Dong-Hua, Afonine, Pavel V., Jakana, Joanita, Wang, Zhao, Jiang, Wen, Adams, Paul D., Schmid, Michael F., Chiu, Wah, King, Jonathan Alan, Haase-Pettingell, CameronGet full text
Published 2017
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8“.../Principal Findings: We have studied the aggregation properties and chaperone interactions of human γD...”
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9by Wang, Yongting, King, Jonathan Alan, Jung, Jinwon, Byeon, In-Ja L., Gronenborn, Angela M.“... and aging of crystallins cause cataracts, the predominant cause of blindness in the world. In human γD...”
Published 2012
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11by Murata, Kazuyoshi, Liu, Xiangan, Danev, Radostin, Jakana, Joanita, Schmid, Michael F., Nagayama, Kuniaki, Chiu, Wah, King, Jonathan Alan“... with advanced image processing methods, we achieved subnanometer resolution for two biological specimens: 2D...”
Published 2015
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12“..., the ability of human TRiC to suppress the aggregation of human γD-crystallin was examined. In addition...”
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