Showing 1 - 20 results of 715 for search 'M.', query time: 0.15s Refine Results
  1. 1
    A unifying model for mTORC1-mediated regulation of mRNA translation
    “...he mTOR complex 1 (mTORC1) kinase nucleates a pathway that promotes cell growth and proliferation...”
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  2. 2
    Presynaptic m1 muscarinic receptors are necessary for mGluR LTD in the hippocampus
    “...To investigate the role of M1 muscarininc acetylcholine receptors (m1 receptors) in metabotropic...”
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  3. 3
    Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
    “...N6-methyladenosine (m6A) is a common modification of mRNA with potential roles in fine-tuning...”
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  4. 4
    The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
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  5. 5
    Rapamycin inhibits mTORC1, but not completely
    by Thoreen, Carson C, Sabatini, David
    Published 2012
    “...Rapamycin is widely used as a complete inhibitor of the mTORC1 nutrient-sensitive signaling complex...”
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  6. 6
    Grounded: Transcriptional Pausing in Naive mESCs
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  7. 7
    Regulation of mTORC1 by amino acids
    by Bar-Peled, Liron, Sabatini, David
    Published 2017
    “...The mechanistic target of rapamycin complex I (mTORC1) is a central regulator of cellular...”
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  8. 8
    An emerging role of mTOR in lipid biosynthesis
    by Laplante, Mathieu, Sabatini, David
    Published 2012
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  9. 9
    mTOR Signaling in Growth Control and Disease
    “...The mechanistic target of rapamycin (mTOR) signaling pathway senses and integrates a variety...”
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  10. 10
    mRNA vaccine delivery using lipid nanoparticles
    “...mRNA vaccines elicit a potent immune response including antibodies and cytotoxic T cells. m...”
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  11. 11
    A Central Role for mTOR in Lipid Homeostasis
    “...The mechanistic target of rapamycin (mTOR) signaling pathway regulates many fundamental metabolic...”
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  12. 12
    mTOR and cancer: many loops in one pathway
    by Efeyan, Alejo, Sabatini, David
    Published 2012
    “...The mammalian target of rapamycin (mTOR) is a master regulator of cell growth and division...”
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  13. 13
    The TSC-mTOR pathway regulates macrophage polarization
    “...Macrophages are able to polarize to proinflammatory M1 or alternative M2 states with distinct...”
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  14. 14
    Dysregulation of mRNA Localization and Translation in Genetic Disease
    “... mechanisms of cytoplasmic mRNA regulation, and how these processes are dysregulated in genetic disease...”
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  15. 15
    Amino acids and mTORC1: from lysosomes to disease
    “...The mechanistic target of rapamycin (mTOR) kinase controls growth and metabolism, and its...”
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  16. 16
    Nutrients versus growth factors in mTORC1 activation
    “...Growth factors and nutrients regulate the mTORC1 [mammalian (or mechanistic) target of rapamycin...”
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  17. 17
    mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin
    “...The mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) protein kinase promotes growth...”
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  18. 18
    Reconsidering Movement of Eukaryotic mRNAs between Polysomes and P Bodies
    “..., it was proposed that translationally silenced eukaryotic mRNAs accumulate in P bodies and can return to active...”
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  19. 19
    Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
    “... to be necessary for amino acid−induced activation of mTORC1. The RagC variants increased raptor binding while...”
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  20. 20
    mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin
    “...The mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) protein kinase promotes growth...”
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