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3von Pillon, Monica C., Lorenowicz, Jessica J., Uckelmann, Michael, Klocko, Andrew D., Mitchell, Ryan R., Chung, Yu Seon, Modrich, Paul, Walker, Graham C., Simmons, Lyle A., Friedhoff, Peter, Guarne, Alba“... replication fidelity 100- to 1000-fold in organisms ranging from bacteria to humans. The MutL protein plays a...”
Veröffentlicht 2015
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4von Ingram, Jessica R., Dougan, Michael, Rashidian, Mohammad, Knoll, Marko, Keliher, Edmund J., Garrett, Sarah, Garforth, Scott, Blomberg, Olga S., Espinosa, Camilo, Bhan, Atul, Almo, Steven C., Weissleder, Ralph, Dougan, Stephanie K., Lodish, Harvey F, Ploegh, Hidde“...Programmed death ligand 1 (PD-L1) is expressed on a number of immune and cancer cells, where it can...”
Veröffentlicht 2018
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5von Ploegh, Hidde, Rosmarin, David M., Carette, Jan E., Olive, Andrew J., Starnbach, Michael N., Brummelkamp, Thijn R.“...-of-function genetic screen in human haploid cells to identify host factors important in C. trachomatis L2...”
Veröffentlicht 2013
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6“...Goldenseal (Hydrastis canadensis L.) is a medicinal plant valued for the treatment of sore eyes...”
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7von Lander, Eric Steven“... by inhibiting the activity of the Niemann–Pick C1-like 1 (NPC1L1) protein. However, whether such inhibition...”
Veröffentlicht 2015
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9von Ryan, Jeremy, Letai, Anthony, Dutta, Sanjib, Chen, T. Scott, Kougentakis, Christos, Keating, Amy E.“... this mechanism in response to diverse signals. The five pro-survival proteins Bcl-x[subscript L], Mcl-1, Bcl-2...”
Veröffentlicht 2017
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10von Yi, Caroline H., Pan, Heling, Seebacher, Jan, Jang, Il-Ho, Hyberts, Sven G., Heffron, Gregory J., Vander Heiden, Matthew G., Yang, Renliang, Li, Fupeng, Locasale, Jason W., Sharfi, Hadar, Zhai, Bo, Rodriguez-Mias, Ricard, Luithardt, Harry, Cantley, Lewis C., Daley, George Q., Asara, John M., Gygi, Steven P., Wagner, Gerhard, Liu, Chuan-Fa, Yuan, Junying“... of acetyl-CoA. Because the antiapoptotic protein Bcl-xL is known to influence mitochondrial metabolism, we...”
Veröffentlicht 2014
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11von Wang, Chao, Yosef, Nir, Gaublomme, Jellert, Wu, Chuan, Lee, Youjin, Clish, Clary B., Kaminski, Jim, Xiao, Sheng, Zu Horste, Gerd Meyer, Pawlak, Mathias, Kishi, Yasuhiro, Joller, Nicole, Karwacz, Katarzyna, Zhu, Chen, Ordovas-Montanes, Maria, Madi, Asaf, Wortman, Ivo, Miyazaki, Toru, Sobel, Raymond A., Park, Hongkun, Regev, Aviv, Kuchroo, Vijay K.“...-pathogenic’ Th17 cell states remain largely unknown. We used single-cell RNA-seq to identify CD5L/AIM as a...”
Veröffentlicht 2016
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12von Feng, Yu-Xiong, Reinhardt, Ferenc, Jin, Dexter X., Sokol, Ethan Samuel, Miller, Daniel Handel, Gupta, Piyush“.... Here we identify the transcription factor CREB3L1 as an essential mediator of PERK's pro-metastatic...”
Veröffentlicht 2018
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13von Prak, Lina, Rayon-Estrada, Violeta, Thiru, Prathapan, Flygare, Johan, Lim, Bing, Zhang, Lingbo, Ph. D. Massachusetts Institute of Technology, Lodish, Harvey F“... that the RNA-binding protein ZFP36L2 is a transcriptional target of the glucocorticoid receptor (GR) in BFU–Es...”
Veröffentlicht 2014
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14von Dutta, Sanjib, Gulla, Stefano, Fire, Emiko, Keating, Amy E., Chen, T. Scott, Grant, Robert A“... and SPOT peptide array analysis—to elucidate specificity determinants for binding to Bcl-x[subscript L...”
Veröffentlicht 2012
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15von Chung, J., Bauer, D. E., Ghamari, A., Nizzi, C. P., Deck, K. M., Kingsley, P. D., Yien, Y. Y., Huston, N. C., Chen, C., Schultz, I. J., Dalton, A. J., Wittig, J. G., Palis, J., Orkin, S. H., Eisenstein, R. S., Cantor, A. B., Paw, B. H., Lodish, Harvey F“..., particularly L-leucine....”
Veröffentlicht 2017
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16von Choi, Yoon Jong, Saez, Borja, Anders, Lars, Hydbring, Per, Stefano, Joanna, Bacon, Nickolas A., Cook, Colleen, Kalaszczynska, Ilona, Signoretti, Sabina, Scadden, David T., Sicinski, Piotr, Young, Richard A.“... receptor Fas and its ligand, FasL. Acute ablation of D-cyclins upregulated these proapoptotic genes and led...”
Veröffentlicht 2017
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17“... into the RNA structure that controls expression of ribosomal proteins L20 and L35 within the Bacillus subtilis...”
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18von Stadanlick, Jason E., Zhang, Zhiqiang, Lee, Sang-Yun, Hemann, Michael, Biery, Matthew, Carleton, Michael O., Zambetti, Gerard P., Anderson, Stephen J., Oravecz, Tamas, Wiest, David L.Volltext
Veröffentlicht 2012
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19von Bass, Adam J., Lawrence, Michael S., Brace, Lear E., Ramos, Alex H., Drier, Yotam, Cibulskis, Kristian, Sougnez, Carrie, Voet, Douglas, Saksena, Gordon, Sivachenko, Andrey, Jing, Rui, Parkin, Melissa, Pugh, Trevor, Verhaak, Roel G., Stransky, Nicolas, Boutin, Adam T., Barretina, Jordi, Solit, David B., Vakiani, Evi, Lander, Eric Steven“... and TCF7L2 found in 3 out of 97 colorectal cancers. Although TCF7L2 encodes TCF4, which cooperates with β...”
Veröffentlicht 2014
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20von Cattie, Douglas John, Richardson, Claire Elissa, Reddy, Kirthi C., Ness-Cohn, Elan M., Droste, Rita, Thompson, Mary Katherine, Gilbert, Wendy, Kim, Dennis H.“... and eIF3l subunits of the translation initiation complex eIF3 result in a 40% extension in lifespan...”
Veröffentlicht 2017
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