Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation

by Danielian, Paul S., Lees, Jacqueline, Landman, A. S.
Published 2015

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

by Huarte, Maite, Guttman, Mitchell, Feldser, David M., Garber, Manuel, Koziol, Magdalena J., Kenzelmann-Broz, Daniela, Khalil, Ahmad M., Zuk, Or, Amit, Ido, Rabani, Michal, Attardi, Laura D., Regev, Aviv, Lander, Eric S., Rinn, John L., Jacks, Tyler E.
Published 2015

LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint

by Sarma, Kavitha, Lee, Jeannie T., Dimitrova, Nadya, Zamudio, Jesse Ray, Jong, Robyn, Soukup, Dylan S., Resnick, Rebecca, Whipple, Amanda Joy, Raj, Arjun, Sharp, Phillip A., Jacks, Tyler E.
Published 2017

Microfluidic platform for characterizing TCR–pMHC interactions

by Stockslager, Max Andrew, Bagnall, Josephine W, Hecht, Vivian Chaya, Hu, Kevin, Aranda-Michel, Edgar C., Payer, Kristofor, Kimmerling, Robert John, Manalis, Scott R
Published 2019

Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis

by Young, Nathan P., Crowley, Denise G., Jacks, Tyler E.
Published 2011

p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis

by Kirsch, David G., Santiago, Philip M., di Tomaso, Emmanuelle, Sullivan, Julie M., Hou, Wu-Shiun, Dayton, Talya Lucia, Jeffords, Laura B., Sodha, Pooja, Mercer, Kim L., Cohen, Rhianna, Takeuchi, Osamu, Korsmeyer, Stanley J., Bronson, Roderick T., Kim, Carla F., Haigis, Kevin M., Jain, Rakesh K., Jacks, Tyler E.
Published 2014

Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers

by Dorans, Kimberly, Chung, Katherine Minjee, Robbins, Rebecca, Tammela, Tuomas, Gocheva, Vasilena, Jacks, Tyler E., Li, Carman Man Chung, Muzumdar, Mandar
Published 2017

E2F4 cooperates with pRB in the development of extra-embryonic tissues

by Lee, Eunice Y., Yuan, Tina L., Danielian, Paul S., West, Julie C., Lees, Jacqueline
Published 2012

PEG–Polypeptide Block Copolymers as pH-Responsive Endosome-Solubilizing Drug Nanocarriers

by Morton, Stephen Winford, Deng, Zhou J., Murphy, Ryan P., Epps, Thomas H., Hammond, Paula T., Quadir, Mohiuddin Abdul, Shopsowitz, Kevin
Published 2015

Quantifying argonaute proteins in and out of GW/P-bodies: Implications in microRNA activities

by Leung, Anthony K. L., Sharp, Phillip A.
Published 2018

The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism

by Lamming, Dudley W., Sabatini, David M., Soliman, Mohamed A., Abdel Rahman, Anas M., Birsoy, Kivanc, Pawling, Judy, Frigolet, Maria E., Lu, Huogen, Fantus, I. George, Pasculescu, Adrian, Zheng, Yong, Dennis, James W., Pawson, Tony
Published 2015

Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome

by Flynn, Ryan A., Almada, Albert Ernesto, Zamudio, Jesse Ray, Sharp, Phillip A.
Published 2014

Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation

by Nicolay, Brandon N., Danielian, Paul S., Kottakis, Filippos, Lapek, John D., Sanidas, Ioannis, Miles, Wayne O., Dehnad, Mantre, Gierut, Jessica J., Manning, Amity L., Morris, Robert, Haigis, Kevin, Bardeesy, Nabeel, Haas, Wilhelm, Dyson, Nicholas J., Lees, Jacquelineb, Tschop, Katrin, Lees, Jacqueline
Published 2016

Cytochrome P450 Drives a HIF-Regulated Behavioral Response to Reoxygenation by C. elegans

by Ma, Dengke, Zheng, Shu, Bhatla, Nikhil, Pender, Corinne Lenore, Horvitz, H. Robert, Rothe, Michael, Menzel, Ralph
Published 2014

Layer-by-Layer Nanoparticles with a pH-Sheddable Layer for in Vivo Targeting of Tumor Hypoxia

by Poon, Zhiyong, Chang, Dongsook, Zhao, Xiaoyong, Hammond, Paula T., Zhao, Xiaoyong
Published 2013

Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition

by Jenney, Anne P., Sorger, Peter K., Jones II, Douglas S., Joughin, Brian Alan, Lauffenburger, Douglas A
Published 2018

A pH-responsive supramolecular polymer gel as an enteric elastomer for use in gastric devices

by Zhu, Jiahua, Nash, Landon D., Maitland, Duncan J., Zhang, Shiyi, Bellinger, Andrew, Glettig, Dean, Barman, Ross, Lee, Young-Ah, Cleveland, Cody, Montgomery, Veronica A., Gu, Li, Langer, Robert S, Traverso, Carlo Giovanni
Published 2017

In vitro and in vivo mRNA delivery using lipid-enveloped pHresponsive polymer nanoparticles

by Su, Xingfang, Fricke, Jennifer, Kavanagh, Daniel G., Irvine, Darrell J.
Published 2013

The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death

by Bock, Florian J., Tanzer, Maria C., Haschka, Manuel D., Krumschnabel, Gerhard, Sohm, Benedicte, Goetsch, Katrin, Kofler, Reinhard, Villunger, Andreas
Published 2015

A plug-and-play ratiometric pH-sensing nanoprobe for high-throughput investigation of endosomal escape

by Ow, Hooisweng, Deng, Zhou, Morton, Stephen Winford, Bonner, Daniel Kenneth, Gu, Li, Hammond, Paula T
Published 2017