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1by Stockslager, Max Andrew, Hecht, Vivian Chaya, Hu, Kevin, Aranda-Michel, Edgar C., Kimmerling, Robert John, Manalis, Scott R, Shaw, Josephine, Payer, Kristofor Robert“... (pMHC) interaction are known to play a central role in determining T cell function in the initial stages...”
Published 2019
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3Extracellular Acidic pH Inhibits Oligodendrocyte Precursor Viability, Migration, and Differentiation“... remyelination potential of oligodendrocytes. Here, we show that acidic extracellular pH, which is characteristic...”
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4“...Acidic extracellular pH is characteristic of the cell microenvironment in several important...”
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5“... of mRNA-based vaccines. The pH-responsive PBAE component was chosen to promote endosome disruption, while...”
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6by McGrogan, Frank Patrick, Swamy, Tushar, Bishop, Sean, Eggleton, Erica E, Porz, Lukas W., Chen, Xinwei, Chiang, Yet-Ming, Van Vliet, Krystyn J“... for an amorphous Li₂S–P₂S₅ Li-ion solid electrolyte. Although low elastic modulus suggests accommodation...”
Published 2017
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7by Jenney, Anne P., Sorger, Peter K., Jones II, Douglas S., Joughin, Brian Alan, Lauffenburger, Douglas A“... the kinase signaling pathways JAK, JNK, p38, and MEK in synovial fibroblasts (SFs), a stromal cell type...”
Published 2018
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9by Ghazi, Phaedra C., Baldwin, Katherine R., Edwards, Amanda, Boukhali, Myriam, Lin, Yi-Jang, Yajnik, Vijay, Kissil, Joseph L., Haas, Wilhelm, Haigis, Kevin M., Lyons, Jesse Stolberg, Brubaker, Douglas, Strasser, Samantha Dale, Suarez Lopez, Lucia, Lauffenburger, Douglas A“... multiomics data implicated increased p21-activated kinase (Pak) signaling as a driver of colitis. Chemical...”
Published 2018
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10p53 null Fluorescent Yellow Direct Repeat (FYDR) mice have normal levels of homologous recombinationby Wiktor-Brown, Dominika M., Sukup-Jackson, Michelle R., Fakhraldeen, Saja A., Hendricks, Carrie A., Engelward, Bevin P.“...The tumor suppressor p53 is a transcription factor whose function is critical for maintaining...”
Published 2014
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11by Brustad, Eric M., Lelyveld, Victor S., Snow, Christopher D., Crook, Nathan, Jung, Sang Taek, Martinez, Francisco M., Scholl, Timothy J., Arnold, Frances H., Jasanoff, Alan Pradip“.... Here, we show that structure-guided directed evolution of the active site of the cytochrome P450‐BM3...”
Published 2015
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12by Jackson, Walker S., Borkowski, Andrew W., Watson, Nicki E., King, Oliver D., Faas, Henryk, Jasanoff, Alan Pradip, Lindquist, Susan“...In man, mutations in different regions of the prion protein (PrP) are associated with infectious...”
Published 2014
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13by Chan, Michael, Song, Yong-Ak, Celio, Chris, Tannenbaum, Steven Robert, Wishnok, John S., Han, Jongyoon“..., we demonstrated a separation of positive and negative peptides and proteins at a given pH in standard...”
Published 2011
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14by Grant, Robert A., Tsao, Ming-Sound, Cannell, Ian Gordon, Merrick, Karl Andrew, Morandell, Sandra M., Grant, Robert A, Cameron, Eleanor Ruth, Hemann, Michael, Yaffe, Michael B, Braun, Christian Joerg“...In normal cells p53 is activated by DNA damage checkpoint kinases to simultaneously control the G1...”
Published 2016
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16by Schmidt, Michael M., Townson, Sharon A., Andreucci, Amy J., King, Bracken Matheny, Schirmer, Emily B., Murillo, Alec J., Dombrowski, Christian, Tisdale, Alison W., Lowden, Patricia A., Masci, Allyson L., Kovalchin, Joseph T., Erbe, David V., Wittrup, Karl Dane, Furfine, Eric S., Barnes, Thomas M.“..., derives from pH-dependent endosomal salvage from degradation, mediated by the neonatal Fc receptor (FcRn...”
Published 2014
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17by Reinhardt, H. Christian, Kim, Jacob S., Ruf, Daniela M., Mitra, Tanya, Couvillon, Anthony D., Yaffe, Michael B., Cannell, Ian Gordon, Reinhardt, H. Christian, Kim, Jacob S., Ruf, Daniela M., Morandell, Sandra M., Jacks, Tyler E, Yaffe, Michael B“... and components of the DNA damage response (DDR) in vivo. The stress-activated p38 mitogen-activated protein...”
Published 2014
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18by Keegan, Caroline, Krutzik, Stephan, Schenk, Mirjam, Scumpia, Phillip O., Pang, Yan Ling Joy, Russell, Brandon S, Lim, Kok Seong, Shell, Scarlet, Prestwich, Erin, Su, Dan, Elashoff, David, Hershberg, Robert M., Bloom, Barry R., Belisle, John T., Fortune, Sarah, Dedon, Peter C, Pellegrini, Matteo, Modlin, Robert L., Lu, Jing,Ph.D.Massachusetts Institute of Technology.Get full text
Published 2020
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19by Amal, Haitham, Gong, Guanyu, Gjoneska, Elizabeta, Lewis, Sarah M, Wishnok, John S., Tsai, Li-Huei, Tannenbaum, Steven R“... of dementia. The missense mutation in the Mapt gene in the P301S mouse model of FTD results in impaired...”
Published 2020
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20by Espelin, Christopher W., Goldsipe, Arthur C., Sorger, Peter K., Lauffenburger, Douglas A., de Graaf, David, Hendriks, Bart S.“... that the ability of a p38 inhibitor to attenuate TNFα production is influenced by local levels of GM-CSF and IL-1β...”
Published 2012
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